Pathobiology and Therapeutics

Total Contact Hours:

67 hours

Course Director:

Paul G. Koles, M.D., Associate Professor, Pathology and Surgery

Course Description:

This course is the introduction to general pathological processes and to basic principles of pharmacology before beginning a detailed study of the physiology, pathology, and pharmacology of each organ system of the human body in the second year.

Course Learning Goals, Assessment, Practice, and Teaching and Learning Activities, and their Integration with the Institutional Educational Objectives:

What does our institution want our graduates to do?	If your students mastered the content of your course, what would they be able to do?	What will students need to do for them and others (peers, professors) to know whether they have achieved this specific learning goal?	How will students get the information they need to learn?
K1, K3 C2 P2	Foundational Knowledge, Path Use the vocabulary of pathology to describe disease.	Vocabulary MCQ exam (36 questions) Comprehensive Term 1 and Term 2 Final Exams	Practice questions: MCQ review sessions Klatt & Kumar’s Review of Pathology Katzung & Trevor’s Board Review of Pharmacology	Study of two textbooks (students independently define 100 essential terms) Lectures: definitions repeated and applied
K1, K3 C2 P2	Foundational Knowledge, Pharm Use the vocabulary of pharmacology to describe interactions between the body and drugs.	Vocabulary MCQ exam (36 questions) Comprehensive Term 1 and Term 2 Final Exams	Practice questions: MCQ review sessions Klatt & Kumar’s Review of Pathology (MCQ review) Katzung & Trevor’s Board Review of Pharmacology (MCQ Review)	Study of two textbooks (students independently define 100 essential terms) Lectures: definitions are repeated and applied
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Path Analyze genetic, anatomic, and laboratory data to make conclusions about the etiology, pathogenesis, pathophysiology, morphology, and clinical features of disease.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Pharm Predict the effects of drugs that use ANS receptors by using knowledge of the anatomy and physiology of the autonomic nervous system.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Pharm Interpret graphic or numerical data to form conclusions about pharmacokinetics, pharmacodynamics, pharmacotherapeutics, and pharmacogenetics.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Pharm Describe mechanisms of action and predict the physiologic effects of autonomic, anti-inflammatory, anticoagulant, antineoplastic, and immune-modulating drugs.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Path (integration) Evaluate a patient’s laboratory data (anatomic and clinical) to determine the appropriate class of drug or specific agent that would benefit that patient.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Application of Knowledge, Pharm (integration) Predict the effects of a specific drug or class of drug on a patient’s disease, including both therapeutic and adverse effects.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Textbook study Live lectures Self-Instruction modules Syllabus MCQ reviews of path/pharm
K1, K2, K3 C2, C3 P1, P2, P3	Learning How to Learn Acquire knowledge through reading Golan and Robbins textbooks, guided by faculty’s learning objectives.	TBL IRAT/GRAT Weekly MCQ exams Final Exam Comprehensive Term 1 and Term 2 Final Exams	Intra-lecture questions based on assigned reading MCQ Review sessions TBL GAPP MCQ reviews of path/pharm	Independent reading of textbooks in preparation for classroom activities, studying with peers, TBL modules, and exams

What does our institution want our graduates to do?

If your students mastered the content of your course, what would they be able to do?

What will students need to do for them and others (peers, professors) to know whether they have achieved this specific learning goal?

How will students get the information they need to learn?

1.
Institutional Objectives

2.
Learning Goals

3.
Assessment
Activities (graded)

4.
Practice/
Feedback Activities (non-graded)

5.
Teaching and Learning Activities

K1, K3

Foundational Knowledge, Path Use the vocabulary of pathology to describe disease.

Vocabulary MCQ exam

(36 questions)

Comprehensive Term 1 and Term 2 Final Exams

Practice questions:

MCQ review sessions
Klatt & Kumar’s Review of Pathology
Katzung & Trevor’s Board Review of Pharmacology

Study of two textbooks

(students independently define 100 essential terms)

Lectures: definitions repeated and applied

K1, K3

Foundational Knowledge, Pharm
Use the vocabulary of pharmacology to describe interactions between the body and drugs.

Vocabulary MCQ exam

(36 questions)

Comprehensive Term 1 and Term 2 Final Exams

Practice questions:

MCQ review sessions
Klatt & Kumar’s Review of Pathology (MCQ review)
Katzung & Trevor’s Board Review of Pharmacology (MCQ Review)

Study of two textbooks

(students independently define 100 essential terms)

Lectures: definitions are repeated and applied

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Path
Analyze genetic, anatomic, and laboratory data to make conclusions about the etiology, pathogenesis, pathophysiology, morphology, and clinical features of disease.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Pharm
Predict the effects of drugs that use ANS receptors by using knowledge of the anatomy and physiology of the autonomic nervous system.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Pharm
Interpret graphic or numerical data to form conclusions about pharmacokinetics, pharmacodynamics, pharmacotherapeutics, and pharmacogenetics.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Pharm Describe mechanisms of action and predict the physiologic effects of autonomic, anti-inflammatory, anticoagulant, antineoplastic, and immune-modulating drugs.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Path (integration)
Evaluate a patient’s laboratory data (anatomic and clinical) to determine the appropriate class of drug or specific agent that would benefit that patient.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Application of Knowledge, Pharm (integration)
Predict the effects of a specific drug or class of drug on a patient’s disease, including both therapeutic and adverse effects.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Textbook study

Live lectures

Self-Instruction modules

Syllabus

MCQ reviews of path/pharm

K1, K2, K3

C2, C3

P1, P2, P3

Learning How to Learn
Acquire knowledge through reading Golan and Robbins textbooks, guided by faculty’s learning objectives.

TBL IRAT/GRAT

Weekly MCQ exams

Final Exam

Comprehensive Term 1 and Term 2 Final Exams

Intra-lecture questions based on assigned reading

MCQ Review sessions

TBL GAPP

MCQ reviews of path/pharm

Independent reading of textbooks in preparation for classroom activities, studying with peers, TBL modules, and exams

Last updated: August 12, 2011