James E. Olson, Ph.D. Professor Professor of Emergency Medicine Address: 182 Cox Institute Phone: (937) 395-8839 E-mail: james.olson@wright.edu University of California, Berkeley, 1978

Research Interests:

• Mechanisms of brain adaptation to edema
• Cellular volume regulation
• Membrane channel activation during apoptosis
• Blood-brain barrier water transport

Visit Dr. Olson's home page

Selected Publications:

Li G, Olson JE (in press) Extracellular ATP activates chloride and taurine conductanes in cultured hippocampal neurons. Neurochemical Research.

Kreisman NR, Olson, JE (2003) Taurine enhances volume regulation in osmotically swollen hippocampal slices. Neuroscience 120:635-642.

Olson JE, Kreisman NR, Lim J, Hoffman B, Schelble Dana, Leasure J (2003) Taurine and cellular volume regulation in the hippocampus, In: Taurine 5 (Lombardini B, Schaffer S, Azuma J, eds), pp 107-114. New York: Kluwer Plenum.

Li G, Liu Y, Olson JE (2002) Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes. Brain Research 925:1-8.

Xu D, Wang L, Olson JE, Lu L (2001) Asymmetrical response of p38 kinase activation to volume changes in primary rat astrocytes, Experimental Biology and Medicine 226:937-933.

Mulkey DK, Henderson III RA, Olson JE, Putnam RW, Dean JB (2001) Oxygen measurements in brainstem slices exposed to normobaric hyperoxia and hyperbaric oxygen. Journal of Applied Physiology 90: 1887-1899.

Chellis M, Olson JE, Augustine J, Hamilton GC (2001) Evaluation of missed diagnoses for patients admitted from the emergency department. Academic Emergency Medicine 8:125-130.

Olson JE, Li G (2000) Osmotic sensitivity of taurine release from hippocampal neuronal and glial cells. In: Taurine 4. Della Corte L, Huxtable RJ, Sgaragli G, Tipton KF, eds), pp 213-218. New York: Plenum.

Irazuzta JE, Olson JE, Kiefaber MP, Wong H (1999) Hypothermia decreases excitatory neurotransmitters release in bacterial meningitis in rabbits. Brain Research 847:143-148.

Olson JE (1999) Osmolyte contents of cultured astrocytes grown in hypoosmotic medium. Biochimica et Biophysica Acts 1453:175-179.

Beetsch JW, Olson JW (1998) Taurine synthesis and cysteine metabolism in cultured rat astrocytes: effects of hyperosmotic exposure. American Journal of Physiology 274:C866-C874.

Olson JE, Putnam RW, Evers JA, Munoz N (1998) Taurine efflux and intracellular pH during astrocyte volume regulation. In: Taurine 3 (Schaffer S, Lombardini B, Huxtable RJ, eds), pp 229-235. New York: Plenum.

Olson JE, Li G (1997) Increased potassium, chloride, and taurine conductances in astrocytes during hypoosmotic swelling. Gila 20:254-261.

Olson JE, Banks M, Evers J, Dimlich RVW (1997) Blood-brain barrier water permeability and osmolyte content during edema development. Academic Emergency Medicine 4:662-673.